Pt-catalyzed tandem epoxide fragmentation/pentannulation of propargylic esters

被引：87

作者：

Pujanauski, Brian G. ^{[1
]}

Prasad, B. A. Bhanu ^{[1
]}

Sarpong, Richmond ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 21期

关键词：

D O I：

10.1021/ja061549m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Pt-catalyzed pentannulation of propargylic esters containing an epoxide moiety has been developed. The present transformation achieves the formation of cyclopentenone products as single diastereomers in good yields. The observed products likely form from pyran intermediates that undergo an oxa-6π electrocyclic ring opening to a functionalized dienone, followed by ring closure with an accompanying acyl shift. Copyright © 2006 American Chemical Society.

引用

页码：6786 / 6787

页数：2

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