Yeasts illustrate the molecular mechanisms of eukaryotic genome evolution

被引：169

作者：

Dujon, Bernard

机构：

[1] Univ Paris 06, Inst Pasteur, URA 2171 CNRS, Unite Genet Mol Levures, F-75724 Paris 15, France

[2] Univ Paris 06, Inst Pasteur, UFR927, F-75724 Paris 15, France

来源：

TRENDS IN GENETICS | 2006年 / 22卷 / 07期

关键词：

D O I：

10.1016/j.tig.2006.05.007

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Hemiascomycetous yeasts have the greatest number of sequenced species for a single phylum, and are at the forefront of evolutionary genomics of eukaryotes. Yeast genomes show the dynamic interplay between the formation and loss of genes and help to characterize the mechanisms involved and their functional and evolutionary consequences. These mechanisms have equivalents in the genomes of multicellular organisms. Yeast genomes show extensive loss of introns and a reduced role of transposable elements, and so probably have a more limited potential to form novel genes and functions than multicellular organisms, possibly explaining their conserved biological and morphological properties despite their considerable evolutionary range.

引用

收藏

页码：375 / 387

页数：13

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