Fucoidan Extracted from Fucus Evanescens Brown Algae Corrects Immunity and Hemostasis Disorders in Experimental Endotoxemia

被引：13

作者：

Kuznetsova, T. A. ^{[1
]}

机构：

[1] Russian Acad Med Sci, Siberian Div, Inst Epidemiol & Microbiol, Immunol Lab, Vladivostok, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2009年 / 147卷 / 01期

关键词：

fucoidans; hemostasis; immunity; cytokines; lipopolysaccharides; COAGULATION; SEPSIS; HEPARIN; TISSUE;

D O I：

10.1007/s10517-009-0445-y

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Fucoidan extracted from brown algae (Fucus evanescens) was used for correction of immunity and hemostasis disorders in experimental endotoxemia induced by injection of LPS. Fucoidan reduced the elevated levels of proinflammatory cytokines (TNF-alpha, IL-1, IL-6) and partially arrested hypercoagulation phenomena, thus improving animal resistance to LPS.

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页码：66 / 69

页数：4

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