homogeneous catalysis;
iron;
ketones;
ligand effects;
transfer hydrogenation;
D O I:
10.1002/asia.200600105
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
Iron complexes generated in situ catalyze homogeneously the transfer hydrogenation of aliphatic and aromatic ketones by utilizing 2-propanol as a hydrogen donor in the presence of base. The influence of different reaction parameters on the catalytic activity is investigated in detail by applying a three-component catalyst system composed of an iron salt, 2,2':6',2"-terpyridine, and PPh3. The scope and limitations of the described catalyst is shown in the reduction of 11 different ketones. In most cases, high conversion and excellent chemoselectivity are obtained. Mechanistic studies indicate a monohydride reaction pathway for the homogeneous iron catalyst.
机构:
Univ Nottingham, Dept Chem, White House Off Sci & Technol Policy, Nottingham NG7 2RD, EnglandUniv Nottingham, Dept Chem, White House Off Sci & Technol Policy, Nottingham NG7 2RD, England
Anastas, PT
Kirchhoff, MM
论文数: 0引用数: 0
h-index: 0
机构:Univ Nottingham, Dept Chem, White House Off Sci & Technol Policy, Nottingham NG7 2RD, England
Kirchhoff, MM
Williamson, TC
论文数: 0引用数: 0
h-index: 0
机构:Univ Nottingham, Dept Chem, White House Off Sci & Technol Policy, Nottingham NG7 2RD, England
机构:
Univ Nottingham, Dept Chem, White House Off Sci & Technol Policy, Nottingham NG7 2RD, EnglandUniv Nottingham, Dept Chem, White House Off Sci & Technol Policy, Nottingham NG7 2RD, England
Anastas, PT
Kirchhoff, MM
论文数: 0引用数: 0
h-index: 0
机构:Univ Nottingham, Dept Chem, White House Off Sci & Technol Policy, Nottingham NG7 2RD, England
Kirchhoff, MM
Williamson, TC
论文数: 0引用数: 0
h-index: 0
机构:Univ Nottingham, Dept Chem, White House Off Sci & Technol Policy, Nottingham NG7 2RD, England