A diversity oriented synthesis of 3′-O-modified nucleoside triphosphates for DNA 'sequencing by synthesis'

被引：22

作者：

Lu, Genliang ^{[1
]}

Burgess, Kevin ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Chem, College Stn, TX 77842 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2006年 / 16卷 / 15期

关键词：

DNA; sequencing; nucleoside; triphosphate; photolabile;

D O I：

10.1016/j.bmcl.2006.05.035

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

The nucleoside triphosphates 1, containing a photochemically cleavable group, and 2, having one that may be cleaved via palladium catalysis, were prepared as a prelude to investigating sequencing of DNA via sequencing by synthesis. (c) 2006 Elsevier Ltd. All rights reserved.

引用

收藏

页码：3902 / 3905

页数：4

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