Productive replication of human adenoviruses in mouse epidermal cells

被引：46

作者：

Ganly, I

Mautner, V

Balmain, A

机构：

[1] CRC Beatson Labs, CRC Dept Med Oncol, Glasgow G61 1BD, Lanark, Scotland

[2] Univ Birmingham, CRC Inst Can Stud, Birmingham B15 2TT, W Midlands, England

来源：

JOURNAL OF VIROLOGY | 2000年 / 74卷 / 06期

关键词：

D O I：

10.1128/JVI.74.6.2895-2899.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In contrast to most cells of mouse origin, cell lines derived from mouse epidermis are permissive for replication of human adenovirus type 5. The extent of epidermal cell differentiation correlated with the level of E1A expression and virus replication. Mouse epidermal cells may provide useful models for cancer therapy using replication-competent human adenoviruses.

引用

收藏

页码：2895 / 2899

页数：5

相关论文

共 23 条

[1] ANALYSIS OF ADENOVIRUS EARLY AND LATE GENE-EXPRESSION IN CULTURED EPIDERMAL-KERATINOCYTES [J].

ANESKIEVICH, BJ ;

LEE, JI ;

TAICHMAN, LB .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1990, 94 (02) :183-186

[2] An adenovirus mutant that replicates selectively in p53-deficient human tumor cells [J].

Bischoff, JR ;

Kim, DH ;

Williams, A ;

Heise, C ;

Horn, S ;

Muna, M ;

Ng, L ;

Nye, JA ;

SampsonJohannes, A ;

Fattaey, A ;

McCormick, F .

SCIENCE, 1996, 274 (5286) :373-376

[3]

BURNS PA, 1991, ONCOGENE, V6, P2363

[4] INFECTION OF MOUSE-LIVER BY HUMAN ADENOVIRUS TYPE-5 [J].

DUNCAN, SJ ;

GORDON, FCA ;

GREGORY, DW ;

MCPHIE, JL ;

POSTLETHWAITE, R ;

WHITE, R ;

WILLCOX, HNA .

JOURNAL OF GENERAL VIROLOGY, 1978, 40 (JUL) :45-61

[5] MOLECULAR-BIOLOGY OF ADENOVIRUS TYPE-2 SEMIPERMISSIVE INFECTIONS .1. VIRAL GROWTH AND EXPRESSION OF VIRAL REPLICATIVE FUNCTIONS DURING RESTRICTED ADENOVIRUS INFECTION [J].

EGGERDING, FA ;

PIERCE, WC .

VIROLOGY, 1986, 148 (01) :97-113

[6] Gene therapy of experimental malignant mesothelioma using adenovirus vectors encoding the HSVtk gene [J].

Esandi, MC ;

vanSomeren, GD ;

Vincent, AJPE ;

vanBekkum, DW ;

Valerio, D ;

Bout, A ;

Noteboom, JL .

GENE THERAPY, 1997, 4 (04) :280-287

[7] REPRESSION OF ADENOVIRUS-E1A ENHANCER ACTIVITY BY A NOVEL ZINC FINGER-CONTAINING DNA-BINDING PROTEIN RELATED TO THE GLI-KRUPPEL PROTEIN [J].

FOGNANI, C ;

DELLAVALLE, G ;

BABISS, LE .

EMBO JOURNAL, 1993, 12 (13) :4985-4992

[8]

Ginsberg HS, 1996, B NEW YORK ACAD MED, V73, P53

[9] A MOUSE MODEL FOR INVESTIGATING THE MOLECULAR PATHOGENESIS OF ADENOVIRUS PNEUMONIA [J].

GINSBERG, HS ;

MOLDAWER, LL ;

SEHGAL, PB ;

REDINGTON, M ;

KILIAN, PL ;

CHANOCK, RM ;

PRINCE, GA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (05) :1651-1655

[10]

Graham F L, 1991, Methods Mol Biol, V7, P109, DOI 10.1385/0-89603-178-0:109