Polymeric Nanoparticles for a Drug Delivery System

被引：52

作者：

Grottkau, Brian E. ^{[1
,2
]}

Cai, Xiaoxiao ^{[3
]}

Wang, Jing ^{[4
]}

Yang, Xingmei ^{[3
]}

Lin, Yunfeng ^{[3
]}

机构：

[1] Harvard Univ, Sch Med, MassGen Hosp Children, Dept Orthopaed Surg, Boston, MA USA

[2] Harvard Univ, Sch Med, Pediat Orthopaed Lab Tissue Engn & Regenerat Med, Boston, MA USA

[3] Sichuan Univ, West China Hosp Stomatol, State Key Lab Oral Dis, Chengdu 610041, Peoples R China

[4] Tongji Univ, Shanghai Peoples Hosp 10, Sch Med, Dept Stomatol, Shanghai 200092, Peoples R China

来源：

CURRENT DRUG METABOLISM | 2013年 / 14卷 / 08期

基金：

国家教育部博士点专项基金资助; 中国国家自然科学基金;

关键词：

Polymeric nanoparticles; PHA; PLGA; PEG-PLGA NANOPARTICLES; BIODEGRADABLE NANOPARTICLES; TARGETED NANOMEDICINES; POLYHYDROXYALKANOATES; BIOCOMPATIBILITY; MICROSPHERES; PARAMETERS; RELEASE; CANCER; PHB;

D O I：

10.2174/138920021131400105

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

In recent years, nanotechnology research has made great strides in the area of pharmacy, especially for drug delivery systems. Polymeric nanoparticles provide significant stability in anti-neoplastic drug research and have demonstrated the ability to solve the problems of therapeutic efficacy and diagnostic sensitivity. In this review, we describe the specific advantages of polymeric nanoparticles and their applications for a drug delivery system. The latest research on PHA-based polymeric nanoparticles and PLGA is also discussed.

引用

页码：840 / 846

页数：7

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