Cellular prion protein expressed by bovine squamous epithelia of skin and upper gastrointestinal tract

被引：15

作者：

Pammer, J

Suchy, A

Rendl, M

Tschachler, E

机构：

[1] Univ Vienna, Sch Med, Dept Dermatol, A-1090 Vienna, Austria

[2] Univ Vienna, Sch Med, Inst Clin Pathol, A-1090 Vienna, Austria

[3] Univ Vet Med, Inst Vet Pathol, Vienna, Austria

来源：

LANCET | 1999年 / 354卷 / 9191期

关键词：

D O I：

10.1016/S0140-6736(99)02800-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Routes of transmission of bovine spongiform encephalopathy have not yet been determined. We show that bovine squamous epithelia of the skin and upper gastrointestinal tract express Prp(c), suggesting that these epithelia may be a target for prion entry and replication.

引用

页码：1702 / 1703

页数：2

共 5 条

[1] Natural and experimental oral infection of nonhuman primates by bovine spongiform encephalopathy agents [J].