Nasopharyngeal carcinoma

被引：295

作者：

Chan, ATC ^{[1
]}

Teo, PML ^{[1
]}

Johnson, PJ ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Clin Oncol, Sir YK Pao Canc Ctr, Shatin, Hong Kong, Peoples R China

来源：

ANNALS OF ONCOLOGY | 2002年 / 13卷 / 07期

关键词：

Epstein-Barr virus; nasopharyngeal carcinoma; review; treatment;

D O I：

10.1093/annonc/mdf179

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Nasopharyngeal carcinoma (NPC) is endemic in southern China where genetic abnormalities and Epstein-Barr virus (EBV) infection are critical in the pathogenesis of the disease, Circulating EBV-DNA has been shown to improve prognostication and monitoring of NPC patients. Radiotherapy is the mainstay treatment for early disease and concurrent cisplatin/radiotherapy has been demonstrated to prolong survival in locoregionally advanced disease. Ongoing studies of targeting agents and immunotherapeutic approaches may further improve treatment results.

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收藏

页码：1007 / 1015

页数：9

相关论文

共 61 条

[1] Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: Phase III randomized intergroup study 0099 [J].

Al-Sarraf, M ;

LeBlanc, M ;

Giri, PGS ;

Fu, KK ;

Cooper, J ;

Vuong, T ;

Forastiere, AA ;

Adams, G ;

Sakr, WA ;

Schuller, DE ;

Ensley, JF .

JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (04) :1310-1317

[2] CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED NASOPHARYNGEAL CARCINOMA - A RADIATION-THERAPY ONCOLOGY GROUP-STUDY [J].

ALSARRAF, M ;

PAJAK, TF ;

COOPER, JS ;

MOHIUDDIN, M ;

HERSKOVIC, A ;

AGER, PJ .

JOURNAL OF CLINICAL ONCOLOGY, 1990, 8 (08) :1342-1351

[3] Activity of paclitaxel by three-hour infusion in Asian patients with metastatic undifferentiated nasopharyngeal cancer [J].

Au, E ;

Tan, EH ;

Ang, PT .

ANNALS OF ONCOLOGY, 1998, 9 (03) :327-329

[4] CHEMOTHERAPY OF METASTATIC AND OR RECURRENT UNDIFFERENTIATED NASOPHARYNGEAL CARCINOMA WITH CISPLATIN, BLEOMYCIN, AND FLUOROURACIL [J].

BOUSSEN, H ;

CVITKOVIC, E ;

WENDLING, JL ;

AZLI, N ;

BACHOUCHI, M ;

MAHJOUBI, R ;

KALIFA, C ;

WIBAULT, P ;

SCHWAAB, G ;

ARMAND, JP .

JOURNAL OF CLINICAL ONCOLOGY, 1991, 9 (09) :1675-1681

[5]

Chan ASC, 2000, CANCER RES, V60, P5365

[6]

CHAN AT, 2000, P AM SOC CLIN ONCOL, V19

[7]

Chan ATC, 1998, CANCER-AM CANCER SOC, V82, P1003, DOI 10.1002/(SICI)1097-0142(19980315)82:6<1003::AID-CNCR1>3.0.CO

[8]

2-F

[9] A PROSPECTIVE RANDOMIZED STUDY OF CHEMOTHERAPY ADJUNCTIVE TO DEFINITIVE RADIOTHERAPY IN ADVANCED NASOPHARYNGEAL CARCINOMA [J].

CHAN, ATC ;

TEO, PML ;

LEUNG, TWT ;

LEUNG, SF ;

LEE, WY ;

YEO, W ;

CHOI, PHK ;

JOHNSON, PJ .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1995, 33 (03) :569-577

[10]

CHAN ATC, 2001, P AM SOC CLIN ONCOL, V20

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