Is Chlamlydia pneumoniae found in spinal fluid samples from multiple sclerosis patients? Conflicting results

被引:30
作者
Kaufman, M
Gaydos, CA
Sriram, S
Boman, J
Tondella, ML
Norton, HJ
机构
[1] Carolinas Med Ctr, Charlotte, NC 28232 USA
[2] Johns Hopkins Univ, Div Infect Dis, Baltimore, MD 21205 USA
[3] Vanderbilt Univ, Med Ctr, Dept Neurol, Nashville, TN 37212 USA
[4] Umea Univ, Dept Virol, SE-90185 Umea, Sweden
[5] Ctr Dis Control & Prevent, Atlanta, GA 30333 USA
来源
MULTIPLE SCLEROSIS | 2002年 / 8卷 / 04期
关键词
Chlamydia pneumoniae; multiple sclerosis; polymerase chain reaction;
D O I
10.1191/1352458502ms815oa
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cerebrospinal fluid samples from controls and patients with multiple sclerosis (MS) were split and sent to laboratories with different experiences for the detection of Chlamydia pneumoniae by polymerase chain reaction. Vanderbilt investigators identified C. pneumoniae in the majority of patients with MS and uncommonly in controls. Laboratories at Johns Hopkins University, University of Ume (a) over circle, and the Centers for Disease Control and Prevention did not identify C. pneumoniae in any of the samples. Conflicting reports of C. pneumoniae detection in the same samples from patients with MS highlight the need to exchange detection techniques among laboratories involved in this controversy.
引用
收藏
页码:289 / 294
页数:6
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