Review article: Pathogenesis and treatment of chronic hepatic encephalopathy

被引：30

作者：

Jalan, R

Seery, JP

TaylorRobinson, SD

机构：

[1] HAMMERSMITH HOSP, ROYAL POSTGRAD MED SCH, ROBERT STEINER MAGNET RESONANCE UNIT, LONDON W12 0HS, ENGLAND

[2] HAMMERSMITH HOSP, ROYAL POSTGRAD MED SCH, GASTROENTEROL UNIT, LONDON W12 0HS, ENGLAND

[3] ROYAL EDINBURGH INFIRM, DEPT MED, EDINBURGH, MIDLOTHIAN, SCOTLAND

[4] ROYAL EDINBURGH INFIRM, CTR LIVER & DIGEST DIS, EDINBURGH, MIDLOTHIAN, SCOTLAND

来源：

ALIMENTARY PHARMACOLOGY & THERAPEUTICS | 1996年 / 10卷 / 05期

关键词：

D O I：

10.1046/j.1365-2036.1996.58200000.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The various treatment strategies for hepatic encephalopathy are compared in the light of the available body of scientific work on the pathogenesis of the syndrome, Data on animal models of hepatic encephalopathy and in vitro studies on brain slices are discussed. Difficulties in extrapolating the results obtained to the human situation are highlighted, while results of human positron emission tomography and magnetic resonance spectroscopy studies are outlined on the background of the potential weaknesses of these non-invasive techniques.

引用

页码：681 / 697

页数：17

共 163 条

[1] NEOMYCIN-SORBITOL AND LACTULOSE IN TREATMENT OF ACUTE PORTAL-SYSTEMIC ENCEPHALOPATHY - CONTROLLED, DOUBLE-BLIND CLINICAL-TRIAL [J].