Rate of progression of mental decline in Alzheimer disease: Summary of European studies

被引：9

作者：

Bracco, L ^{[1
]}

Piccini, C ^{[1
]}

Amaducci, L ^{[1
]}

机构：

[1] Univ Florence, Policlin Careggi, Dept Neurol & Psychiat Sci, I-50134 Florence, Italy

来源：

ALZHEIMER DISEASE & ASSOCIATED DISORDERS | 1998年 / 12卷 / 04期

关键词：

progression; Alzheimer disease; longitudinal studies;

D O I：

10.1097/00002093-199812000-00016

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The aim of this study was to provide an update on the rate of progression in Alzheimer disease. In particular, we conducted a survey on European longitudinal studies that focused on the course of the disease and were performed since 1992. By means of Medline search and review papers and by personal contact with principal investigators, a census of existing studies on natural history of the disease in Europe has been carried out. We present data arising from our search and discuss methodological aspects by comparing data available from U.S. studies on disease progression and implications for clinical trials.

引用

页码：347 / 355

页数：9

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