Helices

被引:136
作者
Chouaieb, Nadia
Goriely, Alain
Maddocks, John H. [1 ]
机构
[1] Ecole Polytech Fed Lausanne, Inst Math B, CH-1015 Lausanne, Switzerland
[2] Inst Preparatoire Etud Ingn El Manar, El Manar 2092, Tunisia
[3] Univ Arizona, Dept Math, Tucson, AZ 85721 USA
[4] Univ Arizona, Program Appl Math, Tucson, AZ 85721 USA
关键词
biomolecules; differential geometry; elasticity; filaments; rods;
D O I
10.1073/pnas.0508370103
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Helices are among the simplest shapes that are observed in the filamentary and molecular structures of nature. The local mechanical properties of such structures are often modeled by a uniform elastic potential energy dependent on bending and twist, which is what we term a rod model. Our first result is to complete the semi-inverse classification, initiated by Kirchhoff, of all infinite, helical equilibria of inextensible, unshearable uniform rods with elastic energies that are a general quadratic function of the flexures and twist. Specifically, we demonstrate that all uniform helical equilibria can be found by means of an explicit planar construction in terms of the intersections of certain circles and hyperbolas. Second, we demonstrate that the same helical center-lines persist as equilibria in the presence of realistic distributed forces modeling nonlocal interactions as those that arise, for example, for charged linear molecules and for filaments of finite thickness exhibiting self-contact. Third, in the absence of any external loading, we demonstrate how to construct explicitly two helical equilibria, precisely one of each handedness, that are the only local energy minimizers subject to a nonconvex constraint of self-avoidance.
引用
收藏
页码:9398 / 9403
页数:6
相关论文
共 47 条
[1]  
[Anonymous], 2013, TREATISE MATH THEORY
[2]  
Antman S. S., 1995, NONLINEAR PROBLEMS E
[3]   KIRCHHOFFS PROBLEM FOR NONLINEARLY ELASTIC RODS [J].
ANTMAN, SS .
QUARTERLY OF APPLIED MATHEMATICS, 1974, 32 (03) :221-240
[4]   CONSTRUCTION OF BACTERIAL FLAGELLA [J].
CALLADINE, CR .
NATURE, 1975, 255 (5504) :121-124
[5]  
Calladine CR., 1992, Understanding DNA
[6]  
Cardou A, 1997, Appl Mech Rev, V50, P1, DOI [10.1115/1.3101684, DOI 10.1115/1.3101684]
[7]   Kirchhoff's problem of helical equilibria of uniform rods [J].
Chouaieb, N ;
Maddocks, J .
JOURNAL OF ELASTICITY, 2004, 77 (03) :221-247
[8]  
Chouaieb N., 2003, THESIS EPFL
[9]   Elastic stability of DNA configurations. II. Supercoiled plasmids with self-contact [J].
Coleman, BD ;
Swigon, D ;
Tobias, I .
PHYSICAL REVIEW E, 2000, 61 (01) :759-770
[10]   THEORY OF THE INFLUENCE OF END CONDITIONS ON SELF-CONTACT IN DNA LOOPS [J].
COLEMAN, BD ;
TOBIAS, I ;
SWIGON, D .
JOURNAL OF CHEMICAL PHYSICS, 1995, 103 (20) :9101-9109