Regulation of pleiotropic drug resistance in yeast

被引：107

作者：

Kolaczkowska, A

Goffeau, A

机构：

[1] Catholic Univ Louvain, Unite Biochim Physiol, B-1348 Louvain, Belgium

[2] Inst Biochem & Mol Biol, PL-50137 Wroclaw, Poland

来源：

DRUG RESISTANCE UPDATES | 1999年 / 2卷 / 06期

关键词：

D O I：

10.1054/drup.1999.0113

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review focuses on the molecular mechanisms involved in the regulation of multiple drug resistance in the model yeast Sacchoromyces cerevisiae and the pathogenic fungus Candida albicans, Recent developments in the study of the transcription factors Pdr I p, Pdr3p and Yap I p are reported. Understanding the molecular basis leading to multiple drug resistance is a prerequisite for the development of new antifungal therapeutics, (C) 1999 Harcourt Publishers Ltd.

引用

收藏

页码：403 / 414

页数：12

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