Vesicle formation at the plasma membrane and trans-Golgi network: The same but different

被引：88

作者：

McNiven, Mark A.

Thompson, Heather M.

机构：

[1] Mayo Clin & Mayo Fdn, Coll Med, Dept Biochem & Mol Biol, Rochester, MN 55905 USA

[2] Mayo Clin & Mayo Fdn, Coll Med, Miles & Shirley Fiterman Ctr Digest Dis, Rochester, MN 55905 USA

来源：

SCIENCE | 2006年 / 313卷 / 5793期

关键词：

D O I：

10.1126/science.1118133

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An elaborate vesicle transport system supports the active exchange of membranes and protein cargo between the plasma membrane and the trans-Golgi network. Many observations suggest that highly conserved mechanisms are used in vesicle formation and scission. Such similarity is found both at the level of the receptor-ligand sequestration process that uses clathrin and associated polymeric and monomeric adaptor proteins, and in the machinery used to deform and vesiculate lipid membranes.

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收藏

页码：1591 / 1594

页数：4

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