Transcriptional silencing in bacteria

被引：26

作者：

Yarmolinsky, M ^{[1
]}

机构：

[1] NCI, Biochem Lab, NIH, Bethesda, MD 20892 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2000年 / 3卷 / 02期

关键词：

D O I：

10.1016/S1369-5274(00)00065-5

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Transcriptional silencing and repression are modes of negative control of gene expression that differ in specificity. Repressors, when present at promoter-specific binding sites, interfere locally with RNA polymerase function. Silencing proteins act by covering a continuous region of DNA, compete with a broader spectrum of proteins and are non-specific with respect to the promoters affected. Studies of transcriptional silencing promise an entree to relatively unexplored areas of prokaryotic biology.

引用

页码：138 / 143

页数：6

共 78 条

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