Membrane sex-steroid receptors in the brain

被引:113
作者
Ramirez, VD
Zheng, J
机构
[1] Dept. of Molec./Integrative Physiol., University of Illinois, 524 Burrill Hall, Urbana, IL 61801
基金
美国国家科学基金会;
关键词
membrane steroid receptors; testosterone; progesterone; estrogen; steroid-BSA conjugates; CNS;
D O I
10.1006/frne.1996.0011
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this review we discuss evidence indicating the existence of specific binding receptor sites for progesterone (P), estrogen (E), and testosterone (T) in neural membranes. The review starts with the methodological approaches for studying receptor binding sites in neural membranes. Second, we examine the physiological and biochemical data supporting the concept of cognate membrane receptors for P, E, and T, the so-called mPR, mER, and mTR. Last, we present an overview emphasizing the concept of continuity of action of steroids on cells from the outer surface to nuclear events. (C) 1996 Academic Press, Inc.
引用
收藏
页码:402 / 439
页数:38
相关论文
共 200 条