Membrane injury by pore-forming proteins

被引：107

作者：

Bischofberger, Mirko ^{[1
]}

Gonzalez, Manuel R. ^{[1
]}

van der Goot, F. Gisou ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Global Hlth Inst, Stn 15, CH-1015 Lausanne, Switzerland

来源：

CURRENT OPINION IN CELL BIOLOGY | 2009年 / 21卷 / 04期

基金：

瑞士国家科学基金会;

关键词：

CHOLESTEROL-DEPENDENT CYTOLYSINS; AMYLOID-BETA-PEPTIDE; PLASMA-MEMBRANE; LISTERIA-MONOCYTOGENES; MITOCHONDRIAL-MEMBRANE; P2X(7) RECEPTOR; STREPTOLYSIN-O; III SECRETION; ALPHA-TOXIN; ATTACK;

D O I：

10.1016/j.ceb.2009.04.003

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The plasma membrane defines the boundary of every living cell, and its integrity is essential for life. The plasma membrane may, however, be challenged by mechanical stress or pore-forming proteins produced by the organism itself or invading pathogens. We will here review recent findings about pore-forming proteins from different organisms, highlighting their structural and functional similarities, and describe the mechanisms that lead to membrane repair, since remarkably, cells can repair breaches in their plasma membrane of up to 10 000 mu m(2).

引用

页码：589 / 595

页数：7

共 68 条

[1] Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis [J].

Abrami, L ;

Leppla, SH ;

van der Goot, FG .

JOURNAL OF CELL BIOLOGY, 2006, 172 (02) :309-320

[2] Host cell traversal is important for progression of the malaria parasite through the dermis to the liver [J].

Amino, Rogerio ;

Giovannini, Donatella ;

Thiberge, Sabine ;

Gueirard, Pascale ;

Boisson, Bertrand ;

Dubremetz, Jean-Francois ;

Prevost, Marie-Christine ;

Ishino, Tomoko ;

Yuda, Masao ;

Menard, Robert .

CELL HOST & MICROBE, 2008, 3 (02) :88-96

[3] Disparate proteins use similar architectures to damage membranes [J].

Anderluh, Gregor ;

Lakey, Jeremy H. .

TRENDS IN BIOCHEMICAL SCIENCES, 2008, 33 (10) :482-490

[4] How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane? [J].

Antignani, Antonella ;

Youle, Richard J. .

CURRENT OPINION IN CELL BIOLOGY, 2006, 18 (06) :685-689

[5] Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AβP (1-40) and (1-42) peptides [J].

Arispe, N ;

Doh, M .

FASEB JOURNAL, 2002, 16 (12) :1526-1536

[6] Pore-forming toxins and cellular non-immune defenses (CNIDs) [J].

Aroian, Raffi ;

van der Goot, F. G. .

CURRENT OPINION IN MICROBIOLOGY, 2007, 10 (01) :57-61

[7] Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles [J].

Birmingham, Cheryl L. ;

Canadien, Veronica ;

Kaniuk, Natalia A. ;

Steinberg, Benjamin E. ;

Higgins, Darren E. ;

Brumell, John H. .

NATURE, 2008, 451 (7176) :350-U13

[8] Activation of the Unfolded Protein Response Is Required for Defenses against Bacterial Pore-Forming Toxin In Vivo [J].

Bischof, Larry J. ;

Kao, Cheng-Yuan ;

Los, Ferdinand C. O. ;

Gonzalez, Manuel R. ;

Shen, Zhouxin ;

Briggs, Steven P. ;

van der Goot, F. Gisou ;

Aroian, Raffi V. .

PLOS PATHOGENS, 2008, 4 (10)

[9] Micro-managing the executioner: pathogen targeting of mitochondria [J].

Blanke, SR .

TRENDS IN MICROBIOLOGY, 2005, 13 (02) :64-71

[10] MG53 nucleates assembly of cell membrane repair machinery [J].

Cai, Chuanxi ;

Masumiya, Haruko ;

Weisleder, Noah ;

Matsuda, Noriyuki ;

Nishi, Miyuki ;

Hwang, Moonsun ;

Ko, Jae-Kyun ;

Lin, Peihui ;

Thornton, Angela ;

Zhao, Xiaoli ;

Pan, Zui ;

Komazaki, Shinji ;

Brotto, Marco ;

Takeshima, Hiroshi ;

Ma, Jianjie .

NATURE CELL BIOLOGY, 2009, 11 (01) :56-U108

← 1 2 3 4 5 6 7 →