Breaking Up Just Got Easier to Do

被引：20

作者：

Klein, Hannah L. ^{[1
]}

Symington, Lorraine S. ^{[2
]}

机构：

[1] NYU, Langone Med Ctr, Dept Biochem, New York, NY 10016 USA

[2] Columbia Univ Coll Phys & Surg, Dept Microbiol, New York, NY 10032 USA

来源：

CELL | 2009年 / 138卷 / 01期

关键词：

DNA-REPAIR; YEAST;

D O I：

10.1016/j.cell.2009.06.039

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The SLX4 protein functions as a platform for catalytic subunits of structure-specific endonucleases. Findings reported in Cell (Fekairi et al., 2009; Svendsen et al., 2009) and in Molecular Cell (Andersen et al., 2009; Mu oz et al., 2009) now identify the human SLX4 and show that in association with the SLX1 endonuclease it directs the symmetric cleavage and resolution of Holliday junctions.

引用

页码：20 / 22

页数：4

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