Cavitand boronic acids mediate highly selective fructose transport

被引：26

作者：

Altamore, TM

Barrett, ES

Duggan, PJ

Sherburn, MS

Szydzik, ML

机构：

[1] Monash Univ, Sch Chem, Melbourne, Vic 3800, Australia

[2] Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 20期

关键词：

D O I：

10.1021/ol0265970

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The synthesis sugar-transport properties of a family of five cavitand rim-appended boronic acids are reported. These conformationally rigid compounds are not observed to leach out of lipophilic membranes, and they exhibit unprecedented fructose to glucose transport selectivities and give higher fluxes than other neutral boronic acids. These properties make the cavitand boronic acids the best artificial fructose transporters described thus far.

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页码：3489 / 3491

页数：3

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