In vitro digestion of novel milk protein ingredients for use in infant formulas:: Research on biological functions

被引：120

作者：

Chatterton, DEW

Rasmussen, JT

Heegaard, CW

Sorensen, ES

Petersen, TE

机构：

[1] Arla Foods Ingredients, DK-8000 Aarhus C, Denmark

[2] Aarhus Univ, Dept Mol Biol, Prot Chem Lab, DK-8000 Aarhus C, Denmark

来源：

TRENDS IN FOOD SCIENCE & TECHNOLOGY | 2004年 / 15卷 / 7-8期

关键词：

D O I：

10.1016/j.tifs.2003.12.004

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Rather than using lengthy clinical studies, in vitro digestion of milk proteins by human neonatal gastric juice at pH values representing those in early neonatal life was investigated. Human milk proteins resisting digestion were immunoglobulins, secretory IgA, alpha(s1)-casein, secretory component, osteopontin and MUC-1. Bovine milk proteins resisting digestion at pH 4.0 were immunoglobulins, BSA, caseins, lactadherin, osteopontin, EPV20 and proteose peptone component 3 (PP3) Some proteins were rapidly digested e.g. CGMP. In vitro digestion provides rapid information regarding the susceptibility of proteins to gastric proteases and is a convenient alternative to clinical studies. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：373 / 383

页数：11

共 49 条

[1]

AHN CI, 1963, J KOREAN MED ASSOC, V6, P948

[2] BIFIDUS GROWTH-PROMOTING ACTIVITY OF A GLYCOMACROPEPTIDE DERIVED FROM HUMAN K-CASEIN [J].