Canine genetics comes of age

被引:159
作者
Ostrander, EA
Galibert, F
Patterson, DF
机构
[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA
[2] Fac Med, UPR 41 CNRS, F-35043 Rennes, France
[3] Univ Penn, Sch Vet Med, Med Genet Sect, Philadelphia, PA 19104 USA
[4] Univ Penn, Sch Vet Med, Ctr Comparat Med Genet, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0168-9525(99)01958-7
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The dog, as human's favored companion, is unique among animal species in providing new insights into human genetic disease. In this review, we will discuss both the breed and the population structure of dogs and why that makes canines amenable to genetic studies. We will review the current state of the map and discuss the particular disease states in which canines stand to make the greatest contribution to medical genetics.
引用
收藏
页码:117 / 124
页数:8
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