Toward an integrated continuum model of cerebral dynamics: the cerebral rhythms, synchronous oscillation and cortical stability

Continuum models of cerebral cortex with parameters derived from physiological data, provide explanations of the cerebral rhythms, synchronous oscillation, and autonomous cortical activity in the gamma frequency range, and suggest possible mechanisms for dynamic self-organization in the brain. Dispersion relations and derivations of power spectral response for the models, show that a low frequency resonant mode and associated travelling wave solutions of the models' equations of state can account for the predominant 1/f spectral content of the electroencephalogram (EEG). Large scale activity in the alpha, beta, and gamma bands, is accounted for by thalamocortical interaction, under regulation by diffuse cortical excitation. System impulse responses can be used to model Event-Related Potentials. Further classes of local resonance may be generated by rapid negative feedbacks at active synapses. Activity in the gamma band around 40 Hz, associated with large amplitude oscillations of pulse density, appears at higher levels of cortical activation, and is unstable unless compensated by synaptic feedbacks. Control of cortical stability by synaptic feedbacks offers a partial account of the regulation of autonomous activity within the cortex. Synchronous oscillation occurs between concurrently excited cortical sites, and can be explained by analysis of wave motion radiating from each of the co-active sites. These models are suitable for the introduction of learning rules-most notably the coherent infomax rule. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.