How I treat the antiphospholipid syndrome

被引：48

作者：

Giannakopoulos, Bill ^{[1
,2
]}

Krilis, Steven A. ^{[1
,2
]}

机构：

[1] St George Hosp, Dept Immunol Allergy & Infect Dis, Kogarah, NSW, Australia

[2] Univ New S Wales, Dept Med, Kogarah, NSW, Australia

来源：

BLOOD | 2009年 / 114卷 / 10期

关键词：

LOW-MOLECULAR-WEIGHT; SYSTEMIC-LUPUS-ERYTHEMATOSUS; RECURRENT PREGNANCY LOSS; UNPROVOKED VENOUS THROMBOEMBOLISM; INTERNATIONAL CONSENSUS STATEMENT; INTENSITY WARFARIN THERAPY; ARTERIAL ORIGIN ESPRIT; DEEP-VEIN-THROMBOSIS; BONE-DENSITY CHANGES; LOW-DOSE ASPIRIN;

D O I：

10.1182/blood-2009-05-220756

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This article discusses how we approach medical decision making in the treatment of the various facets of the antiphospholipid syndrome (APS), including secondary prophylaxis in the setting of venous and arterial thrombosis, as well as treatment for the prevention of recurrent miscarriages and fetal death. The role of primary thromboprophylaxis is also discussed in depth. Great emphasis is given to incorporating the most up-to-date and relevant evidence base both from the APS literature, and from large, recent, randomized controlled trials (RCTs) of primary and secondary thrombotic prophylaxis in the general population setting (ie, the population that has not been specifically investigated for APS). (Blood. 2009; 114: 2020-2030)

引用

页码：2020 / 2030

页数：11

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