Microgravity studies of cells and tissues

被引：41

作者：

Vunjak-Novakovic, G

Searby, N

De Luis, J

Freed, LE

机构：

[1] MIT, Cambridge, MA 02139 USA

[2] NASA, Ames Res Ctr, Moffett Field, CA 94035 USA

[3] Payload Syst Inc, Cambridge, MA USA

来源：

MICROGRAVITY TRANSPORT PROCESSES IN FLUID, THERMAL, BIOLOGICAL, AND MATERIALS SCIENCES | 2002年 / 974卷

关键词：

microgravity; cell culture; tissue engineering; bioreactor; ground studies; flight studies;

D O I：

10.1111/j.1749-6632.2002.tb05927.x

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Controlled in vitro studies of cells and tissues under the conditions of microgravity (simulated on Earth, or actual in space) can improve our understanding of gravity sensing, transduction, and responses in living cells and tissues. This paper discusses the scientific results and practical implications of three NASA-related biotechnology projects: ground and space studies of microgravity tissue engineering (JSC-Houston), and the development of the cell culture unit for use aboard the International Space Station (ARC-Ames).

引用

页码：504 / 517

页数：14

共 28 条

[1] BONTING SL, 1992, ADV SPACE BIOL MED, V2
[2] Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies
Bursac, N
Papadaki, M
Cohen, RJ
Schoen, FJ
Eisenberg, SR
Carrier, R
Vunjak-Novakovic, G
Freed, LE
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1999, 277 (02): : H433 - H444
[3] Carrier RL, 1999, BIOTECHNOL BIOENG, V64, P580, DOI 10.1002/(SICI)1097-0290(19990905)64:5<580::AID-BIT8>3.0.CO
[4] 2-X
[5] Churchill S.E., 1997, FUNDAMENTALS SPACE L
[6] deJong HAA, 1996, AVIAT SPACE ENVIR MD, V67, P463
[7] DELUIS J, 2002, P 51 C INT ASTR FED
[8] Freed L.E., 2000, PRINCIPLES TISSUE EN, P143
[9] Chondrogenesis in a cell-polymer-bioreactor system
Freed, LE
Hollander, AP
Martin, I
Barry, JR
Langer, R
Vunjak-Novakovic, G
[J]. EXPERIMENTAL CELL RESEARCH, 1998, 240 (01) : 58 - 65
[10] Tissue engineering of cartilage in space
Freed, LE
Langer, R
Martin, I
Pellis, NR
VunjakNovakovic, G
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (25) : 13885 - 13890

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