Focus on research: JAK2 mutations in ploycythemia vera - Molecular mechanisms and clinical applications

被引：32

作者：

Tefferi, Ayalew ^{[1
]}

机构：

[1] Mayo Clin Coll Med, Dept Internal Med, Div Hematol, Rochester, MN 55905 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2007年 / 356卷 / 05期

关键词：

D O I：

10.1056/NEJMp068293

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：444 / 445

页数：2

共 5 条

[1] A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera [J].

James, C ;

Ugo, V ;

Le Couédic, JP ;

Staerk, J ;

Delhommeau, F ;

Lacout, C ;

Garçon, L ;

Raslova, H ;

Berger, R ;

Bennaceur-Griscelli, A ;

Villeval, JL ;

Constantinescu, SN ;

Casadevall, N ;

Vainchenker, W .

NATURE, 2005, 434 (7037) :1144-1148

[2] Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders [J].

Jones, AV ;

Kreil, S ;

Zoi, K ;

Waghorn, K ;

Curtis, C ;

Zhang, LY ;

Score, J ;

Seear, R ;

Chase, AJ ;

Grand, FH ;

White, H ;

Zoi, C ;

Loukopoulos, D ;

Terpos, E ;

Vervessou, EC ;

Schultheis, B ;

Emig, M ;

Ernst, T ;

Lengfelder, E ;

Hehlmann, R ;

Hochhaus, A ;

Oscier, D ;

Silver, RT ;

Reiter, A ;

Cross, NCP .

BLOOD, 2005, 106 (06) :2162-2168

[3] A gain-of-function mutation of JAK2 in myeloproliferative disorders [J].

Kralovics, R ;

Passamonti, F ;

Buser, AS ;

Teo, S ;

Tiedt, R ;

Passweg, JR ;

Tichelli, A ;

Cazzola, M ;

Skoda, RC .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (17) :1779-1790

[4] MPLW515L is anovel somatic activating mutation in myelofibrosis with myeloid metaplasia [J].

Pikman, Yana ;

Lee, Benjamin H. ;

Mercher, Thomas ;

McDowell, Elizabeth ;

Ebert, Benjamin L. ;

Gozo, Maricel ;

Cuker, Adam ;

Wernig, Gerlinde ;

Moore, Sandra ;

Galinsky, Ilene ;

DeAngelo, Daniel J. ;

Clark, Jennifer J. ;

Lee, Stephanie J. ;

Golub, Todd R. ;

Wadleigh, Martha ;

Gilliland, D. Gary ;

Levine, Ross L. .

PLOS MEDICINE, 2006, 3 (07) :1140-1151

[5]

Tefferi A, 2005, CELL CYCLE, V4, P1053

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