1,3-asymmetric induction in enolate alkylation reactions of N-protected gamma-amino acid derivatives

被引：46

作者：

Hanessian, S

Schaum, R

机构：

[1] Department of Chemistry, Université de Montréal, Montreal, Que., Succursale Centre-ville

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 02期

关键词：

D O I：

10.1016/S0040-4039(96)02263-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dianions derived from N-TFA and N-Boc gamma-amino acid esters and amides undergo highly stereoselective alpha-alkylation reactions The roles of HMPA, of the cation, the electrophile, and of steric factors were studied. Copyright (C) 1996 Elsevier Science Ltd

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页码：163 / 166

页数：4

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