Lithium triflate (LiOTf) catalyzed efficient and chemoselective tetrahydropyranylation of alcohols and phenols under mild and neutral reaction conditions

被引：71

作者：

Karimi, B ^{[1
]}

Maleki, W ^{[1
]}

机构：

[1] IASBS, Dept Chem, Gava Zang, Zanjan, Iran

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(02)00892-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Different types of alcohols and phenols were effectively converted to the corresponding THP ethers in the presence of DHP and a catalytic amount Of lithium trifluoromethanesulfonate (LiOTf) in refluxing 1,2-dichloroethane under essentially neutral reaction conditions. The method also shoals good chemoselectivity For mono-tetrahydropyranylation of symmetrical diols. (C) 2002 Elsevier Science Ltd. All rights reserved.

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页码：5353 / 5355

页数：3

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