Nanocompatible chemistry toward fabrication of target-specific gold nanoparticles

被引:82
作者
Kannan, Raghuraman
Rahing, Valerie
Cutler, Cathy
Pandrapragada, Ravi
Katti, Kavita K.
Kattumuri, Vijaya
Robertson, J. David
Casteel, Stan J.
Jurisson, Silvia
Smith, Charles
Boote, Evan
Katti, Kattesh V.
机构
[1] Univ Missouri, Dept Radiol, Columbia, MO 65212 USA
[2] Univ Missouri, Dept Chem, Columbia, MO 65212 USA
[3] Univ Missouri, Dept Phys, Columbia, MO 65212 USA
关键词
D O I
10.1021/ja063280c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Nanocompatible chemistry which utilizes a novel nontoxic phosphino amino acid as a reducing agent has resulted in the development of therapeutically useful gold nanoparticles under biologically benign media. Stabilization of gold nanoparticles by the edible gum arabic matrix has provided an effective pathway toward in vivo stable target-specific gold nanoparticles. Copyright © 2006 American Chemical Society.
引用
收藏
页码:11342 / 11343
页数:2
相关论文
共 21 条
[1]  
Balogh L.P., 2003, PHARMACHEM, V2, P94
[2]  
Balogh LP, 2003, J NUCL MED, V44, p305P
[3]   Nanohazards: Knowledge is our first defence [J].
Barnard, AS .
NATURE MATERIALS, 2006, 5 (04) :245-248
[4]   Imaging {Au0-PAMAM} gold-dendrimer nanocomposites in cells [J].
Bielinska, A ;
Eichman, JD ;
Lee, I ;
Baker, JR ;
Balogh, L .
JOURNAL OF NANOPARTICLE RESEARCH, 2002, 4 (05) :395-403
[5]   Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease [J].
Georganopoulou, DG ;
Chang, L ;
Nam, JM ;
Thaxton, CS ;
Mufson, EJ ;
Klein, WL ;
Mirkin, CA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (07) :2273-2276
[6]   The use of gold nanoparticles to enhance radiotherapy in mice [J].
Hainfeld, JF ;
Slatkin, DN ;
Smilowitz, HM .
PHYSICS IN MEDICINE AND BIOLOGY, 2004, 49 (18) :N309-N315
[7]   Quantum-dot/aptamer-based ultrasensitive multi-analyte electrochemical biosensor [J].
Hansen, JA ;
Wang, J ;
Kawde, AN ;
Xiang, Y ;
Gothelf, KV ;
Collins, G .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (07) :2228-2229
[8]   Proteolytic actuation of nanoparticle self-assembly [J].
Harris, Todd I. ;
Maltzahn, Geoffrey von ;
Derfus, Austin M. ;
Ruoslahti, Erkki ;
Bhatia, Sangeeta N. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (19) :3161-3165
[9]   A new class of silica cross-linked micellar core-shell nanoparticles [J].
Huo, Qisheng ;
Liu, Jun ;
Wang, Li-Qiong ;
Jiang, Yingbing ;
Lambert, Timothy N. ;
Fang, Erica .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (19) :6447-6453
[10]   Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer [J].
Kukowska-Latallo, JF ;
Candido, KA ;
Cao, ZY ;
Nigavekar, SS ;
Majoros, IJ ;
Thomas, TP ;
Balogh, LP ;
Khan, MK ;
Baker, JR .
CANCER RESEARCH, 2005, 65 (12) :5317-5324