Are animal tests inherently valid?

被引：7

作者：

Balls, M ^{[1
]}

机构：

[1] FRAME, Nottingham NG1 4EE, England

来源：

ATLA-ALTERNATIVES TO LABORATORY ANIMALS | 2004年 / 32卷

关键词：

animal test; regulatory acceptance; replacement alternative test; validation;

D O I：

10.1177/026119290403201s125

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The proposition that animal tests are inherently valid, merely because they are animal tests, is discussed and is rejected. It is concluded that there is no justifiable reason for subjecting new or substantially modified animal test procedures or testing strategies to a validation process that is any less stringent than that applied to non-animal tests and testing strategies.

引用

页码：755 / 758

页数：4

共 5 条

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Combes, RD .

ATLA-ALTERNATIVES TO LABORATORY ANIMALS, 2000, 28 (01) :81-118

[2]

OConnor AM, 1997, DEV AN VET, V27, P1173

[3]

*OECD, 1996, FINALL REP OECD WORK

[4]

Russell WMS, 1959, Nature, DOI DOI 10.1038/1841675B0

[5] The principles of validation and the ECVAM validation process [J].

Worth, AP ;

Balls, M .

ATLA-ALTERNATIVES TO LABORATORY ANIMALS, 2002, 30 :15-21

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