Studies on chromium(0)-mediated three component cycloaddition reactions

被引：15

作者：

Rigby, JH ^{[1
]}

Heap, CR ^{[1
]}

Warshakoon, NC ^{[1
]}

机构：

[1] Wayne State Univ, Dept Chem, Detroit, MI 48202 USA

来源：

TETRAHEDRON | 2000年 / 56卷 / 15期

关键词：

chromium and compounds; cycloadditions; cycloheptatrienes; diynes;

D O I：

10.1016/S0040-4020(99)01113-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel chromium(0)-promoted three-component alkyne-triene higher-order cycloaddition process is presented. The transformation features tethered alkynes participating in a tandem [6 pi + 2 pi], [6 pi + 2 pi] cycloaddition event with cyclic trienes serving as the third reactant. Isomerically homogeneous products possessing five rings and six stereogenic centers are isolated from this reaction in good to excellent yield. (C) 2000 Elsevier Science Ltd. All rights reserved.

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页码：2305 / 2311

页数：7

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