Hydrophilic diamine ligands for catalytic asymmetric hydrogenation of C=O bonds

被引：27

作者：

Ferrand, A ^{[1
]}

Bruno, M ^{[1
]}

Tommasino, ML ^{[1
]}

Lemaire, M ^{[1
]}

机构：

[1] Lab Catalyse & Synth Organ, CNRS, UMR 5622, SPE, F-69622 Villeurbanne, France

来源：

TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 13期

关键词：

D O I：

10.1016/S0957-4166(02)00332-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Asymmetric hydrogenations of phenylglyoxylate methyl ester and of acetophenone with catalytic amounts of iridium complexes containing hydrophilic chiral C-2-symmetric diamine ligands is reported. E.e. values of up to 68% are observed for complete acetophenone hydrogenation in hydrophilic media. The use of such ligands allowed catalyst recovery without loss of activity and enantioselectivity in at least four hydrogenation cycles. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1379 / 1384

页数：6

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