Guided tissue regeneration in intrabony periodontal defects following treatment with two bioabsorbable membranes in combination with bovine bone mineral graft

被引:20
作者
Vouros, I [1 ]
Aristodimou, E [1 ]
Konstantinidis, A [1 ]
机构
[1] Aristotle Univ Thessaloniki, Sch Dent, Dept Prevent Dent Periodontol & Implant Biol, Thessaloniki, Greece
关键词
bovine bone mineral; collagen barrier; guided tissue regeneration; intrabony defects; periodontal surgery; polylactic acid barrier;
D O I
10.1111/j.1600-051X.2004.00583.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Aim: Comparison of two bioabsorbable barriers (collagen and polylactic acid (PLA) membranes) combined with a bovine bone mineral (BBM) graft, with an access flap procedure (AFP) alone for treating intrabony defects. Material and Methods: Thirty-four subjects participated in this prospective, controlled clinical trial. Baseline clinical examination (probing depth (PD), clinical attachment level (CAL)) of selected sites was performed 2 months after completion of conservative treatment in conjunction with hard-tissue measurements to ascertain the depth of the defect (cementoenamel junction to the bottom of the defects). After randomly dividing patients into three groups (two membrane groups, one control group), full thickness flaps were elevated and exposed root surfaces planed before filling defects with bone graft and positioning a barrier membrane covering the defect. The control group was treated identically except for the barrier and bone graft placement. Clinical treatment outcomes were finally evaluated 12 months after surgery for changes of PD and CAL. Radiographs at baseline and 12 months were compared using non-standardized digital radiography. Results: A mean reduction in PD value of 5.08 mm and mean CAL gain of 4.39 mm occurred in the collagen-BBM group. Corresponding values for the PLA-BBM group were 4.72 and 3.71 mm, while acess flap procedure (AFP) sites produced values of 2.50 and 2.43 mm. All improvements in clinical parameters were statistically significant (p<0.001) within groups for all variables. Both membranes produced statistically greater PD reduction and CAL gain compared with AFP treatment (p<0.05). Comparison between barrier groups failed to reveal any statistically significant difference in probing pocket depth reduction (p=0.56) or in CAL gain (p=0.34). Conclusion: Placement of the two barrier membranes used in the present study in combination with BBM graft significantly improved clinical and radiographic parameters of deep intrabony pockets and proved superior to access flap alone.
引用
收藏
页码:908 / 917
页数:10
相关论文
共 62 条
[1]  
AINAMO J, 1975, INT DENT J, V25, P229
[2]  
Arno A, 1959, J PERIODONTOL, V30, P7, DOI [10.1902/jop.1959.30.1.7, DOI 10.1902/JOP.1959.30.1.7]
[3]   TREATMENT OF MANDIBULAR 3-WALL INTRABONY DEFECTS BY FLAP DEBRIDEMENT AND EXPANDED POLYTETRAFLUOROETHYLENE BARRIER MEMBRANES - LONG-TERM EVALUATION OF 32 TREATED PATIENTS [J].
BECKER, W ;
BECKER, BE .
JOURNAL OF PERIODONTOLOGY, 1993, 64 (11) :1138-1144
[4]   A prospective multi-center study evaluating periodontal regeneration for class II furcation invasions and intrabony defects after treatment with a bioabsorbable barrier membrane: 1-year results [J].
Becker, W ;
Becker, BE ;
Mellonig, J ;
Caffesse, RG ;
Warrer, K ;
Caton, JG ;
Reid, T .
JOURNAL OF PERIODONTOLOGY, 1996, 67 (07) :641-649
[5]   Guided tissue regeneration using a collagen membrane in chronic adult and rapidly progressive periodontitis patients in the treatment of 3-wall intrabony defects [J].
Benque, E ;
Zahedi, S ;
Brocard, D ;
Oscaby, F ;
Justumus, P ;
Brunel, G .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1997, 24 (08) :544-549
[6]   Combined collagen membrane and hydroxyapatite/collagen chondroitin-sulfate spacer placement in the treatment of 2-wall intrabony defects in chronic adult and rapidly progressive periodontitis patients [J].
Benque, E ;
Zahedi, S ;
Brocard, D ;
Oscaby, F ;
Justumus, P ;
Brunel, G .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1997, 24 (08) :550-556
[7]  
BJORN H, 1969, Odontologisk Revy, V20, P165
[8]   Collagen membranes: A review [J].
Bunyaratavej, P ;
Wang, HL .
JOURNAL OF PERIODONTOLOGY, 2001, 72 (02) :215-229
[9]   CLINICAL-EVALUATION OF THE USE OF CITRIC-ACID AND AUTOLOGOUS FIBRONECTIN IN PERIODONTAL SURGERY [J].
CAFFESSE, RG ;
KERRY, GJ ;
CHAVES, ES ;
MCLEAN, TN ;
MORRISON, EC ;
LOPATIN, DE ;
CAFFESSE, ER ;
STULTS, DL .
JOURNAL OF PERIODONTOLOGY, 1988, 59 (09) :565-569
[10]   CLASS-II FURCATIONS TREATED BY GUIDED TISSUE REGENERATION IN HUMANS - CASE-REPORTS [J].
CAFFESSE, RG ;
SMITH, BA ;
DUFF, B ;
MORRISON, EC ;
MERRILL, D ;
BECKER, W .
JOURNAL OF PERIODONTOLOGY, 1990, 61 (08) :510-514