Should all sleep apnoea patients be treated?

被引:18
作者
Montserrat, JM
Barbe, F
Rodenstein, DO
机构
[1] Univ Barcelona, Hosp Clin, Inst Clin Peumol & Cirurg Torac, E-08036 Barcelona, Spain
[2] Hosp Son Dureta, Palma de Mallorca, Spain
[3] Catholic Univ Louvain, Clin Univ St Luc, Brussels, Belgium
关键词
sleep apnoea hypopnoea syndrome; CPAP treatment indications; apnoea hypopnoea index;
D O I
10.1053/smrv.2001.0178
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Sleep apnoea is a condition in which people stop breathing during sleep. A number of studies in general and worker populations have shown that the prevalence of an apnoea-hypopnoea index (AHI) > 10 is in the range of 20%. Subjects with an AHI > 10 that complain of excessive daytime somnolence, tiredness, asphyxic episodes during the night or non-refreshing sleep, among other symptoms, suffer from the sleep apnoea hypopnoea syndrome (SAHS). The prevalence of SAHS is around 4%. Owing to its high prevalence, clinical symptoms, probable secondary cardiovascular consequences and associated social problems, SAHS has a considerable impact on health, management of which is worth considering. Despite the fact that SAHS treatment has been challenged recent studies conclude that nasal continuous positive airway pressure (nCPAP) is undoubtedly effective in clearly symptomatic patients. Its use in clinical practice is adequately supported in the treatment of moderate to severe SAHS. Further studies are needed in order to define the lower range of symptoms to be treated. One of the most important problems encountered in this area results from the combination of two situations. On the one hand, different epidemiological studies have demonstrated that an AHI > 10 without symptoms is present in around 15% of the general population. On the other hand, several studies suggest that having a high AHI, even without secondary symptoms, gives rise to some undesirable effects such as traffic accidents and cardiovascular consequences. In this context, comprehensive epidemiological studies are therefore warranted to define the role of nCPAP treatment especially in those subjects with a high AHI but with few or no symptoms. (C) 2002 Published by Elsevier Science Ltd.
引用
收藏
页码:7 / 14
页数:8
相关论文
共 34 条
  • [1] Evidence of the effectiveness of continuous positive airway pressure in the treatment of sleep apnea/hypopnea syndrome
    Ballester, E
    Badia, JR
    Hernández, L
    Carrasco, E
    de Pablo, J
    Fornas, C
    Rodriguez-Roisin, R
    Montserrat, JM
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (02) : 495 - 501
  • [2] Treatment with continuous positive airway pressure is not effective in patients with sleep apnea but no daytime sleepiness -: A randomized, controlled trial
    Barbé, F
    Mayoralas, LR
    Duran, J
    Masa, JF
    Maimó, A
    Montserrat, JM
    Monasterio, C
    Bosch, M
    Ladaria, A
    Rubio, M
    Rubio, R
    Medinas, M
    Hernandez, L
    Vidal, S
    Douglas, NJ
    Agusti, AGN
    [J]. ANNALS OF INTERNAL MEDICINE, 2001, 134 (11) : 1015 - 1023
  • [3] Automobile accidents in patients with sleep apnea syndrome -: An epidemiological and mechanistic study
    Barbé, F
    Pericás, J
    Muñoz, A
    Findley, L
    Antó, JM
    Agustí, AGN
    Joan, MD
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 158 (01) : 18 - 22
  • [4] Risk of traffic accidents in patients with sleep-disordered breathing: Reduction with nasal CPAP
    Cassel, W
    Ploch, T
    Becker, C
    Dugnus, D
    Peter, JH
    vonWichert, P
    [J]. EUROPEAN RESPIRATORY JOURNAL, 1996, 9 (12) : 2606 - 2611
  • [5] The efficacy of nasal continuous positive airway pressure in the treatment of obstructive sleep apnea syndrome is proven
    Davies, RJO
    Stradling, JR
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2000, 161 (06) : 1775 - 1776
  • [6] Sleep apnea causes daytime hypertension
    Dempsey, JA
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (01) : 1 - 2
  • [7] Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr
    Durán, J
    Esnaola, S
    Rubio, R
    Iztueta, A
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (03) : 685 - 689
  • [8] Neuropsychological function in obstructive sleep apnoea
    Engleman, H
    Joffe, D
    [J]. SLEEP MEDICINE REVIEWS, 1999, 3 (01) : 59 - 78
  • [9] Effect of CPAP therapy on daytime function in patients with mild sleep apnoea/hypopnoea syndrome
    Engleman, HM
    Martin, SE
    Deary, IJ
    Douglas, NJ
    [J]. THORAX, 1997, 52 (02) : 114 - 119
  • [10] Randomized placebo-controlled crossover trial of continuous positive airway pressure for mild sleep apnea/hypopnea syndrome
    Engleman, HM
    Kingshott, RN
    Wraith, PK
    Mackay, TW
    Deary, IJ
    Douglas, NJ
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (02) : 461 - 467