Prion (PrPres) allotypes profiling:: new perspectives from mass spectrometry

被引:4
作者
Maras, B
Barra, D
Schininà, ME
Cardone, F
Pocchiari, M
机构
[1] Univ Roma La Sapienza, Dipartimento Sci Biochim A Rossi Fanelli, Rome, Italy
[2] Ist Super Sanita, Dipartimento Biol Cellulare & Neurosci, I-00161 Rome, Italy
关键词
mass spectrometry; transmissible spongiform encephalopathies; prion protein; allotype profiling;
D O I
10.1255/ejms.602
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
Biochemical methods employed for PrPres allotypes profiling are reviewed and compared with the latest mass spectrometric approaches. Emphasis is put on the advantages offered by a recently proposed electrospray strategy.
引用
收藏
页码:371 / 382
页数:12
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