Complexation of metals with piperazine-containing azamacrocyclic fluorophores

被引：12

作者：

Angelovski, G

Costisella, B

Kolaric, B

Engelhard, M

Eilbracht, P

机构：

[1] Max Planck Inst Mol Physiol, Abt Phys Biochem 3, D-44227 Dortmund, Germany

[2] Univ Dortmund, FB Chem Organ Chem 1, D-44227 Dortmund, Germany

[3] Univ Dortmund, FB Chem Gemeinsame Einrichtungen, NMR Spekt, D-44227 Dortmund, Germany

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 16期

关键词：

D O I：

10.1021/jo049465o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Azamacrocyclic fluorophores containing piperazine units were synthesized using sequential rhodium-catalyzed regioselective hydroformylation-reductive amination. A piperazine unit is introduced into the macrocycles to act simultaneously as electron donor and binding site. The macrocycles chelate divalent cations, either Zn2+ or Co2+, which considerably enhanced fluorescence. Complexation with Zn2+ was additionally confirmed by NMR.

引用

页码：5290 / 5294

页数：5

共 30 条

[1] Synthesis of hydroquinone-, biphenol-, and binaphthol-containing aza macroheterocycles via regioselective hydroformylation and reductive amination [J].