National trends in outcomes among elderly patients with heart failure

被引:70
作者
Kosiborod, Mikhail
Lichtman, Judith H.
Heidenreich, Paul A.
Normand, Sharon-Lise T.
Wang, Yun
Brass, Lawrence M.
Krumholz, Harlan M.
机构
[1] Yale Univ, Sch Med, Dept Epidemiol & Publ Hlth, Sect Chron Dis Epidemiol, New Haven, CT 06520 USA
[2] Univ Missouri, Kansas City, MO 64110 USA
[3] St Lukes Hosp, Mid Amer Heart Inst, Kansas City, MO 64111 USA
[4] Stanford Univ, Dept Med, Stanford, CA 94305 USA
[5] Stanford Univ, VA Palo Alto Hlth Care Syst, Stanford, CA 94305 USA
[6] Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA
[7] Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 USA
[8] Yale New Haven Med Ctr, Ctr Outcomes Res & Evaluat, New Haven, CT 06504 USA
[9] Yale Univ, Sch Med, Dept Neurol, New Haven, CT 06510 USA
[10] VA Connecticut Healthcare Syst, Neurol Serv, West Haven, CT USA
[11] Yale Univ, Sch Med, Sect Hlth Policy & Adm, Dept Epidemiol & Publ Hlth, New Haven, CT USA
[12] Yale Univ, Sch Med, Robert Wood Johnson Clin Scholars Program, New Haven, CT USA
[13] Yale Univ, Sch Med, Sect Cardiovasc Med, Dept Med, New Haven, CT USA
关键词
heart failure; health services research; trends;
D O I
10.1016/j.amjmed.2005.11.019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
PURPOSE: Despite dramatic changes in heart failure management during the 1990s, little is known about the national heart failure mortality trends during this time period, particularly among the elderly. The purpose of this study was to determine temporal trends in outcomes of elderly patients with heart failure between 1992 and 1999. SUBJECTS AND METHODS: We analyzed a national sample of 3,957,520 Medicare beneficiaries aged 65 years or more who were hospitalized with heart failure between 1992 and 1999, assessing temporal trends in 30-day and 1-year all-causemortality and 30-day and 6-month all-cause hospital readmission. In risk-adjusted analyses, mortality and readmission for each year between 1994 and 1999 were compared with the referent year of 1993. RESULTS: Crude 30-day and 1-year mortality decreased slightly (range for 1992-1999: 11.0%-10.3% and 32.5%-31.7%, respectively), whereas 30-day and 6-month readmission increased (10.2%-13.8% and 35.4%-40.3%, respectively). After risk adjustment, there was no change in 30-day mortality between 1993 and 1999 (eg, for 1999 vs 1993, odds ratio [OR] 1.01, 95% confidence interval [CI], 1.00-1.02). One-year mortality was lower in 1994 compared with 1993 (OR 0.91, 95% CI, 0.90-0.92), but data from subsequent years suggested no continuous improvement after 1994 (1999 vs 1993: OR 0.93, 95% CI, 0.92-0.94). Thirty-day readmission increased (1999 vs 1993: OR 1.09, 95% CI, 1.07-1.10), but there was no change in 6-month readmission (1999 vs 1993: OR 1.00, 95% CI, 0.99-1.01). CONCLUSION: We found no substantial improvement in mortality and hospital readmission during the 1990s among elderly patients hospitalized with heart failure. These findings suggest that recent innovations in heart failure management have not yet translated into better outcomes in this population. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码:616.e1 / 616.e7
页数:7
相关论文
共 41 条
  • [1] Trends in postdischarge mortality and readmissions - Has length of stay declined too far?
    Baker, DW
    Einstadter, D
    Husak, SS
    Cebul, RD
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2004, 164 (05) : 538 - 544
  • [2] Mortality trends for 23,505 Medicare patients hospitalized with heart failure in Northeast Ohio, 1991 to 1997
    Baker, DW
    Einstadter, D
    Thomas, C
    Cebul, RD
    [J]. AMERICAN HEART JOURNAL, 2003, 146 (02) : 258 - 264
  • [3] Noncardiac comorbidity increases preventable hospitalizations and mortality among medicare beneficiaries with chronic heart failure
    Braunstein, JB
    Anderson, GF
    Gerstenblith, G
    Weller, W
    Niefeld, M
    Herbert, R
    Wu, AW
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 42 (07) : 1226 - 1233
  • [4] A COMPARISON OF ENALAPRIL WITH HYDRALAZINE ISOSORBIDE DINITRATE IN THE TREATMENT OF CHRONIC CONGESTIVE-HEART-FAILURE
    COHN, JN
    JOHNSON, G
    ZIESCHE, S
    COBB, F
    FRANCIS, G
    TRISTANI, F
    SMITH, R
    DUNKMAN, WB
    LOEB, H
    WONG, ML
    BHAT, G
    GOLDMAN, S
    FLETCHER, RD
    DOHERTY, J
    HUGHES, CV
    CARSON, P
    CINTRON, G
    SHABETAI, R
    HAAKENSON, C
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (05) : 303 - 310
  • [5] A WILCOXON-TYPE TEST FOR TREND
    CUZICK, J
    [J]. STATISTICS IN MEDICINE, 1985, 4 (01) : 87 - 90
  • [6] ADAPTING A CLINICAL COMORBIDITY INDEX FOR USE WITH ICD-9-CM ADMINISTRATIVE DATABASES
    DEYO, RA
    CHERKIN, DC
    CIOL, MA
    [J]. JOURNAL OF CLINICAL EPIDEMIOLOGY, 1992, 45 (06) : 613 - 619
  • [7] *DHHS PHS, 1989, 891260 DHHS PHS
  • [8] Long term survival effect of metoprolol in dilated cardiomyopathy
    Di Lenarda, A
    De Maria, R
    Gavazzi, A
    Gregori, D
    Parolini, M
    Sinagra, G
    Salvatore, L
    Longaro, F
    Bernobich, E
    Camerini, F
    [J]. HEART, 1998, 79 (04) : 337 - 344
  • [9] Doughty RN, 1997, EUR HEART J, V18, P560
  • [10] Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction:: a systematic overview of data from individual patients
    Flather, MD
    Yusuf, S
    Kober, L
    Pfeffer, M
    Hall, A
    Murray, G
    Torp-Pedersen, C
    Ball, S
    Pogue, J
    Moyé, L
    Braunwald, E
    [J]. LANCET, 2000, 355 (9215) : 1575 - 1581