A simple and versatile method for the synthesis of acetals from aldehydes and ketones using bismuth triflate

被引：157

作者：

Leonard, NM ^{[1
]}

Oswald, MC ^{[1
]}

Freiberg, DA ^{[1
]}

Nattier, BA ^{[1
]}

Smith, RC ^{[1
]}

Mohan, RS ^{[1
]}

机构：

[1] Illinois Wesleyan Univ, Dept Chem, Bloomington, IL 61701 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 15期

关键词：

D O I：

10.1021/jo0258249

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acetals are obtained in good yields by treatment of aldehydes and ketones with trialkyl orthoformate and the corresponding alcohol in the presence of 0.1 mol % Bi(OTf)(3).4H(2)O. A simple procedure for the formation of acetals of diaryl ketones has also been developed. The conversion of carbonyl compounds to the corresponding 1,3-dioxolane using ethylene glycol is also catalyzed by Bi(OTf)(3).4H(2)O (1 mol %). Two methods, both of which avoid the use of benzene, have been developed.

引用

页码：5202 / 5207

页数：6

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