An amphiphilic resin-supported palladium catalyst for high-throughput cross-coupling in water

被引：208

作者：

Uozumi, Y

Nakai, Y

机构：

[1] Inst Mol Sci, Okazaki, Aichi 4448585, Japan

[2] Grad Univ Adv Studies, Okazaki, Aichi 4448585, Japan

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 17期

关键词：

D O I：

10.1021/ol0264298

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Suzuki-Miyaura coupling of aryl halides (8 varieties) and aryl- or vinylboronic acids (12 varieties) took place in water in the presence of a palladium complex of an amphiphilic polystyrene-poly(ethylene glycol) copolymer resin-supported N-anchored 2-aza-1,3-bis(diphenylphosphino)propane ligand and potassium carbonate to give uniform and quantitative yields of the corresponding biaryls (96 varieties).

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页码：2997 / 3000

页数：4

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