Synthesis of 1,7-diamino-1,2,6,7-tetradeoxy-2,6-imino-D-glycero-D-ido-heptitol by intramolecular amination of aziridine ring

被引：15

作者：

Chakraborty, TK

Jayaprakash, S

机构：

[1] Indian Inst. of Chemical Technology

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(97)10356-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel intramolecular 6-exo opening of a terminal Boc-protected aziridine ring by a strategically located amino group in the molecule enacted the crucial cyclisation to furnish the key intermediate 10 with requisite deoxyamino imino sugar framework leading to the stereoselective synthesis of 1,7-diamino-1,2,6,7-tetradeoxy-2,6-imino-D-glycero-D-ido-heptitol(5). (C) 1997 Elsevier Science Ltd.

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页码：8899 / 8902

页数：4

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