Arisostatins A and B, new members of tetrocarcin class of antibiotics from Micromonospora sp TP-A0316 -: I.: Taxonomy, fermentation, isolation and biological properties

被引：33

作者：

Furumai, T ^{[1
]}

Takagi, K

Igarashi, Y

Saito, N

Oki, T

机构：

[1] Toyama Prefectural Univ, Biotechnol Res Ctr, Toyama 9390398, Japan

[2] Natl Inst Infect Dis, Shinjuku Ku, Tokyo 1628640, Japan

[3] Tamagawa Univ, Machida, Tokyo 1948610, Japan

来源：

JOURNAL OF ANTIBIOTICS | 2000年 / 53卷 / 03期

关键词：

D O I：

10.7164/antibiotics.53.227

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Arisostatins A and B, new members of tetrocarcin class of antibiotics were isolated from the culture broth of an actinomycete strain. The producing strain, TP-A0316, was identified as Micromonospora sp. Arisostatins were obtained from the culture fluid by solvent extraction and chromatographic purification. They showed antibiotic activity against Gram-positive bacteria and antitumor activity.

引用

页码：227 / 232

页数：6

共 12 条

[1]

Arai T, 1975, CULTURE MEDIA ACTINO

[2]

Hara Mitsunobu, 1999, Proceedings of the American Association for Cancer Research Annual Meeting, V40, P622

[3] Arisostatins A and B, new members of tetrocarcin class of antibiotics from Micromonospora sp TP-A0316 -: II.: Structure determination [J].

Igarashi, Y ;

Takagi, K ;

Kan, Y ;

Fujii, K ;

Harada, K ;

Furumai, T ;

Oki, T .

JOURNAL OF ANTIBIOTICS, 2000, 53 (03) :233-240

[4]

LECHEVALIER H. A., 1970, The Actinomycetales. The Jena International Symposium on Taxonomy, September 1968., P393

[5] CHEMOTAXONOMY OF AEROBIC ACTINOMYCETES - PHOSPHOLIPID COMPOSITION [J].

LECHEVALIER, MP ;

DEBIEVRE, C ;

LECHEVALIER, H .

BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 1977, 5 (04) :249-260

[6] TETROCARCINS, NEW ANTI-TUMOR ANTIBIOTICS .3. ANTI-TUMOR ACTIVITY OF TETROCARCIN-A [J].

MORIMOTO, M ;

FUKUI, M ;

OHKUBO, S ;

TAMAOKI, T ;

TOMITA, F .

JOURNAL OF ANTIBIOTICS, 1982, 35 (08) :1033-1037

[7]

SHIRLING E. B., 1966, INT J SYST BACTERIOL, V16, P313

[8] SIMPLIFIED APPROACH TO IDENTIFICATION OF AEROBIC ACTINOMYCETES BY THIN-LAYER CHROMATOGRAPHY [J].

STANECK, JL ;

ROBERTS, GD .

APPLIED MICROBIOLOGY, 1974, 28 (02) :226-231

[9] TAXONOMIC SIGNIFICANCE OF CELLULAR FATTY-ACID COMPOSITION IN SOME CORYNEFORM BACTERIA [J].

SUZUKI, K ;

KOMAGATA, K .

INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 1983, 33 (02) :188-200

[10] TETROCARCINS, NOVEL ANTI-TUMOR ANTIBIOTICS .2. ISOLATION, CHARACTERIZATION AND ANTI-TUMOR ACTIVITY [J].

TAMAOKI, T ;

KASAI, M ;

SHIRAHATA, K ;

OHKUBO, S ;

MORIMOTO, M ;

MINEURA, K ;

ISHII, S ;

TOMITA, F .

JOURNAL OF ANTIBIOTICS, 1980, 33 (09) :946-950

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