Intracameral bevacizumab for iris rubeosis

被引：151

作者：

Grisanti, Salvatore ^{[1
]}

Biester, Sabine ^{[1
]}

Peters, Swaantje ^{[1
]}

Tatar, Olcay ^{[1
]}

Ziemssen, Focke ^{[1
]}

Bartz-Schmidt, Karl Ulrich ^{[1
]}

机构：

[1] Univ Tubingen, Dept Ophthalmol 1, D-72076 Tubingen, Germany

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 2006年 / 142卷 / 01期

关键词：

D O I：

10.1016/j.ajo.2006.02.045

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

PURPOSE: To determine whether intracameral bevacizumab decreases vascular leakage from iris rubeosis in patients with neovascular glaucoma. DESIGN: Interventional case series. METHODS: The study included six eyes of three patients with secondary neovascular glaucoma due to proliferative diabetic retinopathy (n = 2) or ischemic central retinal vein occlusion (n = 1). All patients received an intracameral injection of 1.0 mg bevacizumab. Morphologic changes and vascular leakage were investigated prospectively by iris fluorescein angiography. RESULTS: Decrease in leakage was detected as early as one day after injection. No inflammation was observed. No relapse was seen within the follow-up of four weeks. CONCLUSION: Intraocular injection of bevacizumab may provide an additional strategy for the treatment of iris rubeosis in neovascular glaucoma.

引用

页码：158 / 160

页数：3

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