Structures of new cucurbitane-type triterpenes and glycosides, karavilagenins and karavilosides, from the dried fruit of Momordica charantia L. in Sri Lanka

被引：73

作者：

Nakamura, Seikou ^{[1
]}

Murakami, Toshiyuki ^{[1
]}

Nakamura, Junko ^{[1
]}

Kobayashi, Hisanori ^{[1
]}

Matsuda, Hisashi ^{[1
]}

Yoshikawa, Masayuki ^{[1
]}

机构：

[1] Kyoto Pharmaceut Univ, Yamashina Ku, Kyoto 6078412, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2006年 / 54卷 / 11期

关键词：

Momordica charantia; karavilagenin; karaviloside; Sri Lanka; cucurbitane-type triterpene; medicinal foodstuff;

D O I：

10.1248/cpb.54.1545

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

Three new cucurbitane-type triterpene called karavilagenins A, B, and C and five new cucurbitane-type triterpene glycosides called karavilosides I, II, III, IV, and V were isolated from the dried fruit of Sri Lanka Momordica charantia L. (Cucurbitaceae) together with two known cucurbitane-type triterpenes, 19(R)-methoxy-5 beta,19-epoxycucurbita-6,23-dien-3 beta,25-diol and 5,19-epoxycucurbita-6,23-diene-3,25-diol, and nine known cucurbitane-type triterpene glycosides, goyaglycosides-b, -c, and -d, and mornordicosides F-1, F-2, G, I, K, and L. The structures of karavilagenins and karavilosides were elucidated on the basis of chemical and physicochemical evidence.

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页码：1545 / 1550

页数：6

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