The N-butylcarbamate derivative of galantamine acts as an allosteric potentiating ligand on α7 nicotinic receptors in hippocampal neurons -: Clinical implications for treatment of Alzheimer's disease

被引：15

作者：

Popa, Rodica V.

Pereira, Edna F. R.

Lopes, Cristiane

Maelicke, Alfred

Albuquerque, Edson X. ^{[1
]}

机构：

[1] Univ Maryland, Sch Med, Dept Pharmacol & Expt Therapeut, Baltimore, MD 21201 USA

[2] Galantos Pharma GmbH, Biotechnikum Goldgrube, Mainz, Germany

来源：

JOURNAL OF MOLECULAR NEUROSCIENCE | 2006年 / 30卷 / 1-2期

关键词：

D O I：

10.1385/JMN:30:1:227

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：227 / 232

页数：6

共 27 条

[1] Memantine blocks α7*nicotinic acetylcholine receptors more potently than N-methyl-D-aspartate receptors in rat hippocampal neurons [J].

Aracava, Y ;

Pereira, EFR ;

Maelicke, A ;

Albuquerque, EX .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2005, 312 (03) :1195-1205

[2] Galantamine prevents apoptosis induced by β-amyloid and thapsigargin:: involvement of nicotinic acetylcholine receptors [J].

Arias, E ;

Alés, E ;

Gabilan, NH ;

Cano-Abad, MF ;

Villarroya, M ;

García, AG ;

López, MG .

NEUROPHARMACOLOGY, 2004, 46 (01) :103-114

[3]

Bachus R, 1999, PHARMACOGENETICS, V9, P661

[4] PHARMACOKINETICS OF GALANTHAMINE IN HUMANS AND CORRESPONDING CHOLINESTERASE INHIBITION [J].

BICKEL, U ;

THOMSEN, T ;

WEBER, W ;

FISCHER, JP ;

BACHUS, R ;

NITZ, M ;

KEWITZ, H .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1991, 50 (04) :420-428

[5] Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice [J].

Capsoni, S ;

Giannotta, S ;

Cattaneo, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (19) :12432-12437

[6]

Carlson NG, 1998, J NEUROBIOL, V35, P29, DOI 10.1002/(SICI)1097-4695(199804)35:1<29::AID-NEU3>3.0.CO

[7]

2-D

[8] Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease - Characteristics and treatment [J].

Chung, JA ;

Cummings, JL .

NEUROLOGIC CLINICS, 2000, 18 (04) :829-+

[9]

Corey-Bloom J, 2003, INT J CLIN PRACT, V57, P219

[10] Global prevalence of dementia: a Delphi consensus study [J].

Ferri, CP ;

Prince, M ;

Brayne, C ;

Brodaty, H ;

Fratiglioni, L ;

Ganguli, M ;

Hall, K ;

Hasegawa, K ;

Hendrie, H ;

Huang, YQ ;

Jorm, A ;

Mathers, C ;

Menezes, PR ;

Rimmer, E ;

Scazufca, M .

LANCET, 2005, 366 (9503) :2112-2117

← 1 2 3 →