Effects of edaravone on reperfusion injury in patients with acute myocardial infarction

被引：119

作者：

Tsujita, K

Shimomura, H

Kawano, H

Hokamaki, J

Fukuda, M

Yamashita, T

Hida, S

Nakamura, Y

Nagayoshi, Y

Sakamoto, T

Yoshimura, M

Arai, H

Ogawa, H

机构：

[1] Fukuoka Tokushukai Med Ctr, Dept Cardiol, Kasuga, Fukuoka 8160864, Japan

[2] Kumamoto Univ, Dept Cardiovasc Med, Grad Sch Med Sci, Kumamoto, Japan

[3] Kumamoto Univ, Div Intens Care Unit, Grad Sch Med Sci, Kumamoto, Japan

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2004年 / 94卷 / 04期

关键词：

D O I：

10.1016/j.amjcard.2004.05.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This clinical pilot study was a randomized, controlled, open-label study in 80 patients with acute myocardial infarction and was designed to examine the effects of a novel free radical scavenger, edaravone. Administration of edaravone before myocardial reperfusion was associated with smaller enzymatic infarcts and better clinical outcome. (C) 2004 by Excerpta Medico, Inc.

引用

页码：481 / 484

页数：4

共 14 条

[1] STRONG ATTENUATION OF ISCHEMIC AND POSTISCHEMIC BRAIN EDEMA IN RATS BY A NOVEL FREE-RADICAL SCAVENGER [J].