High incidence of penicillin resistance amongst clinical isolates of Streptococcus pneumoniae in northern Palestine

被引:3
作者
Adwan, K [1 ]
Abu-Hasan, N [1 ]
Hamdan, A [1 ]
Al-Khalili, S [1 ]
机构
[1] An Najah Natl Univ, Dept Biol Sci, Nablus, Israel
关键词
D O I
10.1099/00222615-48-12-1107
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
One hundred and thirteen consecutive isolates of Streptococcus pneumoniae were collected in Nablus, Palestine between March and Aug. 1997 from children,vith acute lower respiratory tract infections. Resistance rates were: penicillin 88%, cefuroxime 85%, erythromycin 63%, tetracycline 45%, chloramphenicol 27% and ofloxacin 2%. Resistances to erythromycin and cefuroxime were significantly associated with penicillin resistance. Ofloxacin may be useful against pneumococci resistant to traditional antimicrobial agents. Factors associated with penicillin resistance included hospitalisation and previous use of beta-lactam antibiotics.
引用
收藏
页码:1107 / 1110
页数:4
相关论文
共 18 条
[1]  
Arason VA, 1996, BMJ-BRIT MED J, V313, P387
[2]  
Chong CY, 1997, ACTA PAEDIATR JAPON, V39, P317
[3]   Nasopharyngeal colonization in southern Israel with antibiotic-resistant pneumococci during the first 2 years of life: Relation to serotypes likely to be included in pneumococcal conjugate vaccines [J].
Dagan, R ;
Melamed, R ;
Muallem, M ;
Piglansky, L ;
Yagupsky, P .
JOURNAL OF INFECTIOUS DISEASES, 1996, 174 (06) :1352-1355
[4]   Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: Results of a 30-center national surveillance study [J].
Doern, GV ;
Brueggemann, A ;
Holley, HP ;
Rauch, AM .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (05) :1208-1213
[5]   SUSCEPTIBILITY OF STREPTOCOCCUS-PNEUMONIAE TO PENICILLIN - A PROSPECTIVE MICROBIOLOGICAL AND CLINICAL-STUDY [J].
GARCIALEONI, ME ;
CERCENADO, E ;
RODENO, P ;
DEQUIROS, JCLB ;
MARTINEZHERNANDEZ, D ;
BOUZA, E .
CLINICAL INFECTIOUS DISEASES, 1992, 14 (02) :427-435
[6]  
Huang FY, 1997, J FORMOS MED ASSOC, V96, P414
[7]   Antibiotic resistance among clinically important Gram-positive bacteria in the UK [J].
Johnson, AP .
JOURNAL OF HOSPITAL INFECTION, 1998, 40 (01) :17-26
[8]   EMERGENCE OF MULTIPLE-ANTIBIOTIC-RESISTANT STREPTOCOCCUS-PNEUMONIAE IN HONG-KONG [J].
KAM, KM ;
LUEY, KY ;
FUNG, SM ;
YIU, PP ;
HARDEN, TJ ;
CHEUNG, MM .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (12) :2667-2670
[9]   ANTIBIOTIC-RESISTANCE OF CLINICAL ISOLATES OF STREPTOCOCCUS-PNEUMONIAE IN GREECE [J].
KANAVAKI, S ;
KARABELA, S ;
MARINIS, E ;
LEGAKIS, NJ .
JOURNAL OF CLINICAL MICROBIOLOGY, 1994, 32 (12) :3056-3058
[10]   PNEUMOCOCCAL RESISTANCE TO ANTIBIOTICS [J].
KLUGMAN, KP .
CLINICAL MICROBIOLOGY REVIEWS, 1990, 3 (02) :171-196