Consequences of Early Experiences and Exposure to Oxytocin and Vasopressin Are Sexually Dimorphic

被引：107

作者：

Carter, C. Sue ^{[1
]}

Boone, Ericka M. ^{[1
,3
]}

Pournajafi-Nazarloo, Hossein ^{[1
]}

Bales, Karen L. ^{[2
]}

机构：

[1] Univ Illinois, Dept Psychiat, Brain Body Ctr, Chicago, IL 60612 USA

[2] Univ Calif Davis, Dept Psychol, Davis, CA 95616 USA

[3] NIDA, NIH, DHHS, Bethesda, MD 20892 USA

来源：

DEVELOPMENTAL NEUROSCIENCE | 2009年 / 31卷 / 04期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

Oxytocin; Vasopressin; Pitocin; Sex differences; Early experience; Prairie voles; FEMALE PRAIRIE VOLES; DEVELOPMENTAL EXPOSURE; PARTNER PREFERENCES; SEX-DIFFERENCES; MATERNAL-CARE; FETAL-BRAIN; RECEPTOR; EXPRESSION; BEHAVIOR; HYPOTHALAMUS;

D O I：

10.1159/000216544

中图分类号：

Q [生物科学];

学科分类号：

090105 [作物生产系统与生态工程];

摘要：

In the socially monogamous prairie vole, we have observed that small changes in early handling, as well as early hormonal manipulations can have long-lasting and sexually dimorphic effects on behavior. These changes may be mediated in part by changes in parental interactions with their young, acting on systems that rely on oxytocin (OT) and arginine vasopressin (AVP). Knowledge of both endogenous and exogenous influences on systems that rely on OT and AVP may be helpful in understanding sexually dimorphic developmental disorders, such as autism, that are characterized by increased anxiety and deficits in social behavior. Copyright (C) 2009 S. Karger AG, Basel

引用

页码：332 / 341

页数：10

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