Irisin in humans: recent advances and questions for future research

被引:69
作者
Bostrom, Pontus A. [1 ]
Manuel Fernandez-Real, Jose [2 ,3 ,4 ]
Mantzoros, Christos [5 ,6 ]
机构
[1] Karolinska Inst, Dept Cell & Mol Biol, S-10401 Stockholm, Sweden
[2] Hosp Girona, Sect Diabet Endocrinol & Nutr, Girona, Spain
[3] Hosp Girona, IDIBGI, Girona, Spain
[4] CIBERobn, Madrid, Spain
[5] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Endocrinol Diabet & Metab, Boston, MA 02215 USA
[6] Harvard Univ, Sch Med, Boston VA Healthcare Syst, Endocrinol Sect, Boston, MA 02130 USA
来源
METABOLISM-CLINICAL AND EXPERIMENTAL | 2014年 / 63卷 / 02期
关键词
CIRCULATING LEVELS; ADIPOSE-TISSUE; MESSENGER-RNA; EXERCISE; FNDC5; EXPRESSION; MUSCLE; OBESE; SERUM; PLASMA;
D O I
10.1016/j.metabol.2013.11.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:178 / 180
页数:3
相关论文
共 25 条
[1]   Alterations of irisin concentrations in saliva and serum of obese and normal-weight subjects, before and after 45 min of a Turkish bath or running [J].
Aydin, Suleyman ;
Aydin, Suna ;
Kuloglu, Tuncay ;
Yilmaz, Musa ;
Kalayci, Mehmet ;
Sahin, Ibrahim ;
Cicek, Demet .
PEPTIDES, 2013, 50 :13-18
[2]   A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis [J].
Bostroem, Pontus ;
Wu, Jun ;
Jedrychowski, Mark P. ;
Korde, Anisha ;
Ye, Li ;
Lo, James C. ;
Rasbach, Kyle A. ;
Bostroem, Elisabeth Almer ;
Choi, Jang Hyun ;
Long, Jonathan Z. ;
Kajimura, Shingo ;
Zingaretti, Maria Cristina ;
Vind, Birgitte F. ;
Tu, Hua ;
Cinti, Saverio ;
Hojlund, Kurt ;
Gygi, Steven P. ;
Spiegelman, Bruce M. .
NATURE, 2012, 481 (7382) :463-U72
[3]   Serum irisin levels in new-onset type 2 diabetes [J].
Choi, Yeon-Kyung ;
Kim, Mi-Kyung ;
Bae, Kwi Hyun ;
Seo, Hyun-Ae ;
Jeong, Ji-Yun ;
Lee, Won-Kee ;
Kim, Jung-Guk ;
Lee, In-Kyu ;
Park, Keun-Gyu .
DIABETES RESEARCH AND CLINICAL PRACTICE, 2013, 100 (01) :96-101
[4]   Irisin and FNDC5 in retrospect An exercise hormone or a transmembrane receptor? [J].
Erickson, Harold P. .
ADIPOCYTE, 2013, 2 (04) :289-293
[5]   Effects of Lipid-Lowering Drugs on Irisin in Human Subjects In Vivo and in Human Skeletal Muscle Cells Ex Vivo [J].
Gouni-Berthold, Ioanna ;
Berthold, Heiner K. ;
Huh, Joo Young ;
Berman, Reena ;
Spenrath, Nadine ;
Krone, Wilhelm ;
Mantzoros, Christos S. .
PLOS ONE, 2013, 8 (09)
[6]   FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise [J].
Huh, Joo Young ;
Panagiotou, Grigorios ;
Mougios, Vassilis ;
Brinkoetter, Mary ;
Vamvini, Maria T. ;
Schneider, Benjamin E. ;
Mantzoros, Christos S. .
METABOLISM-CLINICAL AND EXPERIMENTAL, 2012, 61 (12) :1725-1738
[7]   Identification of evolutionarily conserved non-AUG-initiated N-terminal extensions in human coding sequences [J].
Ivanov, Ivaylo P. ;
Firth, Andrew E. ;
Michel, Audrey M. ;
Atkins, John F. ;
Baranov, Pavel V. .
NUCLEIC ACIDS RESEARCH, 2011, 39 (10) :4220-4234
[8]  
Kraemer RR, 2013, HORM METAB RES
[9]   Expression of the Irisin Precursor FNDC5 in Skeletal Muscle Correlates With Aerobic Exercise Performance in Patients With Heart Failure [J].
Lecker, Stewart H. ;
Zavin, Alexandra ;
Cao, Peirang ;
Arena, Ross ;
Allsup, Kelly ;
Daniels, Karla M. ;
Joseph, Jacob ;
Schulze, P. Christian ;
Forman, Daniel E. .
CIRCULATION-HEART FAILURE, 2012, 5 (06) :812-818
[10]   Lower circulating irisin is associated with type 2 diabetes mellitus [J].
Liu, Jian-Jun ;
Wong, Melvin D. S. ;
Toy, Wan Ching ;
Tan, Clara S. H. ;
Liu, Sylvia ;
Ng, Xiao Wei ;
Tavintharan, Subramaniam ;
Sum, Chee Fang ;
Lim, Su Chi .
JOURNAL OF DIABETES AND ITS COMPLICATIONS, 2013, 27 (04) :365-369