May the force be with you: Myosin-X in phagocytosis.

被引：9

作者：

Chavrier, P ^{[1
]}

机构：

[1] Inst Curie, Sect Rech, F-75005 Paris, France

来源：

NATURE CELL BIOLOGY | 2002年 / 4卷 / 07期

关键词：

D O I：

10.1038/ncb0702-e169

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Engulfment of pathogens by phagocytosis requires the coordination of actin assembly and progressive 'zippering' of pseudopodial membranes around the particle. Recent work shows that Myosin-X, which binds phosphatidylinositol-3-OH kinase (PI(3) K) products through its pleckstrin homology (PH) domains, is required for phagocytosis, thereby providing a molecular basis for the function of PI(3) K in pseudopod extension.

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页码：E169 / E171

页数：3

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