Anaerobic biofilm infections in cystic fibrosis

被引：30

作者：

Costerton, JW ^{[1
]}

机构：

[1] Montana State Univ, Ctr Biofilm Engn, Bozeman, MT 59717 USA

来源：

MOLECULAR CELL | 2002年 / 10卷 / 04期

关键词：

D O I：

10.1016/S1097-2765(02)00698-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Pseudomonas aeruginosa is an important pathogen that infects the lungs of cystic fibrosis patients. A paper published in the October issue of Developmental Cell (Yoon et al., 2002) proves that the bacterial cells in the lung live in anaerobic biofilms and adopt a metabolic pattern and a phenotype that differ significantly from those of test tube-grown cells, and even from those of aerobic biofilms.

引用

页码：699 / 700

页数：2

共 4 条

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Greenberg, EP .

NATURE, 2000, 407 (6805) :762-764

[3]

Worlitzsch D, 2002, J CLIN INVEST, V109, P317, DOI 10.1172/JCI0213870

[4] Pseudomonas aeruginosa anaerobic respiration in biofilms:: Relationships to cystic fibrosis pathogenesis [J].

Yoon, SS ;

Hennigan, RF ;

Hilliard, GM ;

Ochsner, UA ;

Parvatiyar, K ;

Kamani, MC ;

Allen, HL ;

DeKievit, TR ;

Gardner, PR ;

Schwab, U ;

Rowe, JJ ;

Iglewski, BH ;

McDermott, TR ;

Mason, RP ;

Wozniak, DJ ;

Hancock, REW ;

Parsek, MR ;

Noah, TL ;

Boucher, RC ;

Hassett, DJ .

DEVELOPMENTAL CELL, 2002, 3 (04) :593-603

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